Job Description
Dementia is the greatest health challenge of our century.
To date there is no way to prevent it or even slow its progression, and there is an urgent need to fill the knowledge gap in our basic understanding of the diseases that cause it.
The UK Dementia Research Institute (UK DRI) is the biggest UK initiative driving forward research to fill this gap.
We are a globally leading multidisciplinary research institute of 700 staff investigating the spectrum of neurodegenerative disorders causing dementia, with laboratory-based research groups located at University College London, the University of Cambridge, Cardiff University, Edinburgh University, Imperial College London and King’s College London.
Researchers at the UK DRI King's College use innovative approaches to explore the biological mechanisms involved in neurodegenerative diseases. Their goal is to defeat dementia by uncovering vital new knowledge that will lead to the design of smarter diagnostics and effective treatments. The team aim to understand the fundamental biological processes involved in dementia at a molecular level – and to use that knowledge to design new ways to diagnose and treat disease more precisely.
Professor Jernej Ule is seeking an undergraduate student to work on an EMY placement for a year, joining a team working on the mechanisms of amyotrophic lateral sclerosis caused by mutations in RNA binding proteins. The group focuses on transcriptomic approaches to study RNP assembly and its defects in disease.
The post holder will contribute to the project, in particular the culture of cellular models of disease, transcriptomic studies of protein-RNA interactions and analysis of resulting datasets.
The post is based at the UK DRI, https://ukdri.ac.uk/, Maurice Wohl Clinical Neuroscience Institute on the Denmark Hill Campus
QualificationsWorking towards BSc in Neuroscience or equivalent biological field
SkillsKey Responsibilities
- Perform laboratory work to optimise the efficiency of our preclinical studies.
- Deliver high-quality data from our preclinical studies including:
- Image tissues using slide scanning and confocal microscopes
- Undertake image analysis using advanced analytical software tools
- An ability to work independently and within a team
- Attention to detail and high standards of accuracy in all work
- Conscientious and organised
- Ability to time manage appropriately
- Willing to work occasionally during weekends and bank holidays
Essential criteria
- Quantitative image analytical software and statistical analyses
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